An autopsy case of systemic lupus erythematosus complicating leukocytosis, amegakaryocytic thrombocytopenia, interstitial pneumonitis, and pleulitis.
نویسندگان
چکیده
منابع مشابه
Cell-mediated amegakaryocytic thrombocytopenia associated with systemic lupus erythematosus.
We studied a patient with a rare complication of amegakaryocytic thrombocytopenia (AMT) associated with systemic lupus erythematosus (SLE). To investigate the underlying pathogenesis of AMT, the effects of peripheral blood T cells and serum on human megakaryocyte progenitor cells were studied using in vitro coculture techniques. Mononuclear bone marrow cells (2 X 10(5) from normal donors produc...
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متن کاملThrombocytopenia in Systemic Lupus Erythematosus
The aim of the study was to examine the clinical characteristics and prognosis according to severity of thrombocytopenia and response to treatment for thrombocytopenia in patients with systemic lupus erythematosus (SLE). We retrospectively evaluated 230 SLE patients with thrombocytopenia, and reviewed their clinical data and laboratory findings. Thrombocytopenia was defined as platelet counts u...
متن کاملSuccessful treatment of amegakaryocytic thrombocytopenia with eltrombopag in a patient with systemic lupus erythematosus (SLE).
Systemic lupus erythematosus (SLE) is an inflammatory connective tissue disease mediated by a deregulated immune system and aberrant production of proinflammatory cytokines leading to multiorgan and tissue damage. Thrombocytopenia is a common complication in patients with SLE, with a prevalence that ranges from 7–30%.1-5 The 2 main mechanisms of thrombocytopenia in SLE are increased platelet de...
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EDWINA LAWSON, KATHARINE BOND, DUNCAN CHURCHILL, KAREN WALKER-BONE Department of Genitourinary Medicine, Royal Sussex County Hospital, Brighton and Brighton and Sussex Medical School, Euan Keat Education Centre, Princess Royal Hospital, Haywards Heath, UK Accepted 22 December 2008 Correspondence to: Karen Walker-Bone, Euan Keat Education Centre, Princess Royal Hospital, Lewes Road, Haywards Hea...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Immunology
سال: 1996
ISSN: 0911-4300,1349-7413
DOI: 10.2177/jsci.19.223